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However, weight loss averages 46% at 14 mg, significantly lower than seen with newer trials

Methods Specimens Keloid and normal skin samples were obtained from patients who underwent plastic surgery for keloids or reconstructive surgery for patients without keloids

Therefore, these findings further support the observation that low IGF-1 preferentially benefits females, and suggest that a potentially broad therapeutic window to target IGF-1R signaling may exist in females, with greater benefit possible by initiating at even younger ages than implemented in this study

They allow prescribers and patients to have careful discussions